EXAMINE THIS REPORT ON SODIUM PENTOBARBITAL SDS

pentobarbital decreases effects of sufentanil SL by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Intently. Coadministration of CYP3A4 inducers may lower sufentanil concentrations and efficacy, probably precipitating withdrawal syndrome in people who may have created Bodily dependence to sufentanil. Discontinuation